Comparison of our quantitative SPECT (single photon emission computed
tomography) reconstruction (right) with the conventional reconstruction
(left) for the 3-D Hoffman brain model. The reconstruction is of
128x128x32 array size.
Our quantitative reconstruction is fully analytical in numerical
calculation and statistical in modeling the Poisson noise and
minimizing the cost function. A unique feature of our approach is
that the transmission scans are not needed (althought transmission
scans are usually required for photon attenuation compensation in
SPECT).
By the NIH R01-NS33853 support, quantitative brain SPECT with optimized
fan-beam collimation, without transmission scans and in an ultrafast
speed has been established. For details, please see our publication in
IEEE Transactions on Medical Imaging, February, 2005.